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KMID : 0869620210380020185
Journal of Korean Society of Hospital Pharmacists
2021 Volume.38 No. 2 p.185 ~ p.194
Analysis of Clinical Pharmacist Interventions in the Cardio-Surgical Intensive Care Unit
Sohn You-Min

Ko Min-Ji
Park Hyo-Jung
Lee Jae-Hyun
Lee Yong-Seok
Lee Hu-Kyoung
Kim Jeong-Mee
Cho Yang-Hyun
Min Myung-Sook
Abstract
Background : It has been reported that clinical pharmacists¡¯ participation in the multidisciplinary intensive care unit (ICU) team reduces the number of medication errors and improves the clinical outcome. However, studies assessing the role of pharmacists in a cardio-surgical ICU (CSICU) are limited. The aim of this study was to analyze pharmacologic interventions and identify pharmacologic problems that require pharmacist intervention in a CSICU.

Methods : The research was conducted by retrospectively reviewing the electronic medical records of patients aged 18 years or older who were admitted to the CSICU of Samsung Medical Center from April 1 2019 to June 30 2019.

Results : During the study, the clinical pharmacist monitored 12,021 drug prescriptions for 205 patients and conducted 379 pharmacologic interventions. The most common pharmacologic intervention recommended by the pharmacist was nutritional support (19.0%), followed by therapeutic drug monitoring (TDM) (18.5%) and provision of drug information (14.8%). The most frequently mediated group of drugs was antibiotics (31.1%), and the causes for pharmacologic intervention of antibiotics were mostly TDM (51.7%) and inappropriate dosage (20.3%). The intervention rate of ¡®pain, sedation and delirium-related drugs¡¯ was 17.2%, while the intervention rate of ¡®antiarrhythmics, anticoagulant, and antiplatelet agents¡¯ was 13.2%. The most common reason for intervention in both groups was missed prescriptions, followed by adverse drug events and inappropriate dosages. The acceptance rate of intervention was 92.2%.

Conclusion : Clinical pharmacists¡¯ participation in the ICU has enabled active drug prescription monitoring, proper nutrition support, and TDM. The acceptance rate of intervention is high. The CSICU requires pharmacologic intervention of pain, sedation and delirium-related drugs specific to critically ill patients, as well as drugs indicated for cardio-surgery.
KEYWORD
Clinical pharmacist, Intervention, Cardio-surgical intensive care unit
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